Using A.I. to Detect Breast Cancer That Doctors Miss

Hungary has become a major testing ground for A.I. software to spot cancer, as doctors debate whether the technology will replace them in medical jobs.

Inside a dark room at Bács-Kiskun County Hospital outside Budapest, Dr. Éva Ambrózay, a radiologist with more than two decades of experience, peered at a computer monitor showing a patients mammogram. Two radiologists had previously said the X-ray did not show any signs that the patient had breast cancer. But Dr. Ambrózay was looking closely at several areas of the scan circled in red, which artificial intelligence software had flagged as potentially cancerous. This is something, she said. She soon ordered the woman to be called back for a biopsy, which is taking place within the next week. Advancements in A.I. are beginning to deliver breakthroughs in breast cancer screening by detecting the signs that doctors miss. So far, the technology is showing an impressive ability to spot cancer at least as well as human radiologists, according to early results and radiologists, in what is one of the most tangible signs to date of how A.I. can improve public health. Hungary, which has a robust breast cancer screening program, is one of the largest testing grounds for the technology on real patients. At five hospitals and clinics that perform more than 35,000 screenings a year, A.I. systems were rolled out starting in 2021 and now help to check for signs of cancer that a radiologist may have overlooked. Clinics and hospitals in the United States, Britain and the European Union are also beginning to test or provide data to help develop the systems. A.I. usage is growing as the technology has become the center of a Silicon Valley boom, with the release of chatbots like ChatGPT showing how A.I. has a remarkable ability to communicate in humanlike prose — sometimes with worrying results. Built off a similar form used by chatbots that is modeled on the human brain, the breast cancer screening technology shows other ways that A.I. is seeping into everyday life. Widespread use of the cancer detection technology still faces many hurdles, doctors and A.I. developers said. Additional clinical trials are needed before the systems can be more widely adopted as an automated second or third reader of breast cancer screens, beyond the limited number of places now using the technology. The tool must also show it can produce accurate results on women of all ages, ethnicities and body types. And the technology must prove it can recognize more complex forms of breast cancer and cut down on false-positives that are not cancerous, radiologists said. The A.I. tools have also prompted a debate about whether they will replace human radiologists, with makers of the technology facing regulatory scrutiny and resistance from some doctors and health institutions. For now, those fears appear overblown, with many experts saying the technology will be effective and trusted by patients only if it is used in partnership with trained doctors. And ultimately, A.I. could be lifesaving, said Dr. László Tabár, a leading mammography educator in Europe who said he was won over by the technology after reviewing its performance in breast cancer screening from several vendors. I am dreaming about the day when women are going to a breast cancer center and they are asking, Do you have A.I. or not? he said.